The Brighton to London line. The 07:44 train. Carriages packed with commuters. A woman applies her make-up. Another occupies her time observing the people around her. A husband and wife share an affectionate gesture. Further along, a woman flicks through a glossy magazine. Then, abruptly, everything changes: a man has a heart attack, and cant be resuscitated; the train is The Brighton to London line. The 07:44 train. Carriages packed with commuters. A woman applies her make-up. Another occupies her time observing the people around her. A husband and wife share an affectionate gesture. Further along, a woman flicks through a glossy magazine. Then, abruptly, everything changes: a man has a heart attack, and cant be resuscitated; the train is stopped, an ambulance called. For at least three passengers on the 07:44 on that particular morning, life will never be the same again. Lou witnesses the mans final moments. Anna and Lou share a cab when they realise the train is going nowhere fast. Anna is Karens best friend. And Karen? Karens husband is the man who dies.